2022 NFL Schedule – Full list of opening bet odds for Week 1

Caesars Sportsbook has published the 2022 NFL schedule. The Week 1 slate will offer plenty of opportunities for bettors to place calls.

The reigning Super Bowl champion Los Angeles RamsAll are welcome Josh AllenThe Buffalo BillsTo SoFi Stadium, Sept. 8 to kick off the season New! Denver BroncosQB Russell WilsonSeattle Seahawks will face off at Lumen Field in Seattle

You can find the latest NFL odds right below.

Caesars Sportsbook provides all odds.


Week 1 Lines

2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Buffalo Billsat Los Angeles Rams
Thursday, 8:20 p.m. ET, SoFi Stadium in Inglewood, CA


Line: Rams (-11)
Money line Rams (-120), Bills (+100)
Over/Under: 52.5 Points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1San Francisco 49ersat Chicago Bears
Sunday, 1:05 p.m ET, Soldier Field, Chicago, Ill.


Line: 49ers (-6)
Money line 49ers (-270), Bears (+1220).
Over/Under: 43 points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1New England Patriotsat Miami Dolphins
Sunday, 1:05 p.m ET, Hard Rock Stadium, Miami Gardens, Fla.


Line: Dolphins
Money line Dolphins (-150), Patriots (+1130)
Over/Under: 44.5 points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1New Orleans SaintsAt Atlanta Falcons
Sunday, 1:05 p.m ET, Mercedes-Benz Stadium, Atlanta, GA


LineSaints (-3)
Money line Saints (-170), Falcons (+145)
Over/Under: 42.5 Points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Baltimore RavensAt New York Jets
Sunday, 1.05 PM ET, MetLife Stadium East Rutherford, N.J.


Line: Ravens (-4)
Money line Ravens (-190), Jets (+160)
Over/Under: 45.5 Points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Pittsburgh SteelersAt Cincinnati Bengals
Sunday, 1.05 p.m. ET, Paul Brown Stadium Cincinnati, Ohio


Line: Bengals (-6)
Money line Bengals (-270), Steelers (+220)
Over/Under: 44 points



2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Cleveland Brownsat Carolina Panthers
Sunday, January 5, 2005, Bank of America Stadium in Charlotte, NC


LineBrowns (-4.5).
Money line Browns (-200), Panthers (+170)
Over/Under: 43.5 Points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Philadelphia Eaglesat Detroit Lions
Sunday, 13:05 ET, Ford Field Detroit, Mich.


LineEagles (-3.5).
Money line Eagles (-200), Lions (+170)
Over/Under: 47 points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Indianapolis Coltsat Houston Texans
Sunday, 1.05 p.m. ET, NRG Stadium Houston, Texas


LineColts (-7.5).
Money line Colts (+380), Texans (+300).
Over/Under: 45 points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Jacksonville Jaguarsat Washington Commanders
Sunday, January 5, 2005, Fedex Field in Landover, Md.


Line: Commanders (-4.5)
Money line Commanders (-210), Jaguars (-175)
Over/Under: 58.5 points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Kansas City Chiefsat Arizona Cardinals
Sunday, April 25, 2019, 4:25 PM ET State Farm Stadium Glendale, Ariz.


Line: Chiefs (-3)
Money line Chiefs (-160), Cardinals (+140)
Over/Under: 55 points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Green Bay Packersat Minnesota Vikings
Sunday, April 25, at 4:25 p.m. ET, U.S. Bank Stadium Minneapolis, Minn.


Line: Packers (-1.5).
Money line Packers (-125), Vikings (+1105)
Over/Under: 48.0 points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Los Angeles Chargersat Las Vegas Raiders
Sunday, April 25, 2019, 4:25 p.m. ET, Allegiant Stadium Paradise Nevada


LineChargers (-4)
Money line Raiders (+160), Chargers -190
Over/Under: 51.5 points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1New York Giantsat Tennessee Titans
Sunday, 4:25 p.m ET, Nissan Stadium, Nashville, Tenn.


Line: Titans (-6.5)
Money line Titans (+300), Giants (+240)
Over/Under: 44 points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Tampa Bay Buccaneersat Dallas Cowboys
Sunday, 8:30 p.m ET, At&T Stadium, Arlington, Texas


Line: Buccaneers (-2.5)
Money line Buccaneers (-135), Cowboys (+115)
Over/Under: 52 points


2022 NFL Schedule - Full list of opening bet odds for Week 12022 NFL Schedule - Full list of opening bet odds for Week 1Denver Broncosat Seattle Seahawks
Monday, 7:30 pm ET CenturyLink Field Seattle (Washington).


Line: Broncos (-3.5)
Money line Broncos (-180), Seahawks (+155)
Over/Under: 41.5 points

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