Scotland wing Darcy Graham is anticipated to be out till February with a knee damage.
The 25-year-old will miss Edinburgh’s upcoming matches with Saracens, Castres, Glasgow Warriors, Zebre and Sharks.
The primary match of Scotland’s Six Nations is away to England on 4 February (16:45 GMT).
Graham went off injured through the first half of Edinburgh’s loss to Munster on Friday.
The wing has scored 80 factors in 33 Assessments for Scotland and been with Edinburgh since 2017.
Edinburgh go to Saracens within the first of two Champions Cup conferences of the perimeters on Sunday.
Prop Pierre Schoeman says he hopes the opener “helps us to fireplace up”.
“The stress is rather more on us to be at our greatest, whether or not that is within the carry, the contact space or set-piece,” the Scotland worldwide mentioned.
“It is virtually like Check-match rugby for these large European video games, particularly in opposition to Saracens, who’re on kind.
“I do know a few of their gamers are going to come back again filled with confidence to membership rugby after the autumn Assessments and they’re going to wish to show themselves.
“You’ll be able to’t have weak moments or lack of focus in these video games as a result of good high quality sides like that can sniff you out and catch you.”