|Venue:Principality Stadium in Cardiff Date:Saturday, 12 Februar Kick-off:14:15 GMT|
|Coverage: You can watch live on BBC One and BBC iPlayer online, starting at 16:00 GMT. Also, listen to BBC Radio 5 live sports extras, BBC Radio Wales, BBC Radio Cymru, and BBC Radio Scotland. Text commentary is available on BBC Sport website or app.|
Coach Wayne Pivac will make Jac Morgan, an uncapped flanker, his debut against Wales in the Six Nations.
Morgan, 22 years old, joins Ross Moriarty in the back row that lost to Ireland. Ellis Jenkins and Aaron Wainwright also dropped out.
Ospreys duo Owen Watkin & Alex Cuthbert will replace Josh Adams & Johnny McNicholl in the other alterations.
Adams is out with a tight calf.
Captain Dan Biggar will be making his 100th international appearance, while centre Jonathan Davies will reach the same milestone if it is not him on the bench.
Morgan will become Wales' second cap after Dewi lake, the hooker.
Morgan, a former Wales Under-20s captain, switched to Ospreys from Scarlets for the 2021-22 seasons and has been a strong flanker in the Welsh domestic league.
Openside flanker Basham will switch to number seven, while Moriarty will pack down between them and Wainwright will drop to the bench.
Moriarty, 27, was able to play his 50th international. He had been on the Dublin bench since October 2021 when he sustained a shoulder injury.
Wales currently has no injured British and Irish Lions back rowers Justin Tipuric or Josh Navidi, Taulupe Faleau and Dan Lydiate.
Pivac said, “Jac will be making his debut and is someone who's really impressed us during training.”
He's worked very hard and gives us a lot physicality. And he's very adept with the ball.
“With Ross having more game and training time, we believe he is the right man to start.”
Watkin was named as the outside centre partner for Nick Tompkins following Adams' injury. Willis Halaholo, who suffered a hamstring injury in the first defeat, is out of commission.
Cuthbert joined Ospreys as an Exeter player in the summer of 2021. He will be playing in his 50th international, winning his 49th Wales cap. This will go along with his Lions test match against Australia in 2013.
He will play his first Six Nations game for five years, his last tournament appearance being against England in Cardiff in 2017, where he was defeated 21-16.
The 31 year-old made a comeback from the wilderness, making a try against Fiji in November 2021.
Biggar will make his 1997th Wales appearance, along with three Lions test in South Africa in 2021. Davies could win his 94th Wales cap in addition to his six Lions tests.
Pivac said, “To have a hundred Test matches for any player from any nation is a remarkable achievement.”
“It is an indication of their hard work and dedication, as well as the sacrifices they have made over the years to get to this point.
“I am happy for both those players to achieve that and to do so on the same day.
“They have played many Test matches together in past – it will be amazing to see them both out on the field at some point.”
Wales: L Williams; Cuthbert. Watkin. Tompkins. ReesZammit. Biggar (capt), T Williams. W Jones. Elias. Francis. Rowlands. Beard. Basham. Morgan. Moriarty.
Replacements:Lake, G Thomas. D Lewis. S Davies. Wainwright. G Davies. Sheedy.