|Venue: Cardiff Arms Park Date:Saturday, April 30, Time:12:00 BST
|Coverage:You can watch live on S4C and BBC Red Button. Listen live via BBC Radio Wales, BBC Sounds or via the BBC Sport app and website. Report on BBC Sport's website and app.
As they try to achieve their best Women’s Six Nations finish in 13 Years, Wales has made eight changes to their starting lineup.
All impact players SionedHarries, Alex Callender and Kelsey Jones are included in the pack, as is Cara Hope, Cara Hope and Donna Rose.
Niamh Terry begins at full-back. Kerin Lake is back at the centre. Robyn Wilkins, Ffion Lewis, and Ffion Lewis are preferred at half-back.
Captain Siwan Lilicra moves to the second row to accommodate Harries at number 8.
Experienced prop Caryl Thomas, and Lleucu George, the utility back, could make their first campaign appearances.
Elinor Snowsill is out of matchday 23. Gwenllian Cyrs is out due to injury.
Kayleigh Powell, Carys Phillips and Carys Williams, who played in the four previous games, were named as the replacements.
Wales is aiming for a third victory on Super Saturday. They have already beaten Scotland and Ireland in the first two rounds.
Their last win of three or more matches was 2009, when they finished second and won Triple Crown.
The Azzurri will be also looking to finish their campaign with a win in Parma over Scotland last weekend.
Due to the shorter format of the Six Nations, the sides didn't meet last year. However, Italy won the 2020 contest 19-15 at Cardiff.
Since then, a lot has happened. 12 members of the Wales squad have become fully-professionals at the beginning of this year. Twelve others have signed retainer agreements.
Italy has also taken steps to professionalize their players in a World Cup Year, announcing 25 central contracts earlier this month.
After heavy defeats against England and France, Ioan Cunningham, Wales' head coach, knows that Italy will be a tough opponent.
“We know it will be a difficult day at the office. Cunningham said that Italy is a great team and that we must be mentally and physically ready for anything.
“We want to end with three wins. That is what this group deserves after working so hard all season.”
Cunningham said, “It's important that we build cohesion while trying different combinations of starting lines-ups.
“There are some players who should be given the chance to play in this final match, or in the 23 after having done well in training.
“It's wonderful to see Kelsey Jones and Caryl Thomas starting after a long-term injuries. Niamh Terry should be able to demonstrate her full-back skills and Cara Hope deserves a start for the first time in the season.
“Sioned Haries has made a significant impact each time that she has been involved, and forms part of an extremely strong backrow. Ffion was again a major player in the game against France. Robyn and she are looking great together.
Wales: Niamh Terry; Lisa Neumann, Hannah Jones, Kerin Lake, Jasmine Joyce; Robyn Wilkins, Ffion Lewis; Cara Hope, Kelsey Jones, Donna Rose, Siwan Lillicrap (capt), Gwen Crabb, Alisha Butchers, Alex Callender, Sioned Harries
Replacements: Carys Phillips,Caryl Thomas, Cerys Hale, Natalia John, Bethan Lewis, Keira Bevan, Lleucu George, Kayleigh Powell.